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      Editorial

      editorial
      Revista Peruana de Medicina Experimental y Salud Pública
      Instituto Nacional de Salud

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          Abstract

          To determine the frequency of vertical transmission of hepatitis B antigen (HB5 Ag) from asymptomatic carrier mothers in Taiwan to their offspring, HB5 Ag was sought by radioimmunoassay and complement fixation. Of 158 babies born to carrier mothers, antigenemia developed in 63; 51 of these antigenemic babies had become antigen positive within the six months of life. Three inter-related factors were found to increase the risk that antigenemia would develop in the infant: a high maternal complement-fixation titer for HB5 Ag: presence of HB5 Ag in the baby's umbilical-cord blood: and antigenemia in siblings. In contrast to previous studies, these findings indicate that vertical transmission from carrier mothers frequently occurs, at least in Taiwan, and may partially explain Taiwan's high prevalence of HB5 Ag.

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          Author and article information

          Journal
          rpmesp
          Revista Peruana de Medicina Experimental y Salud Pública
          Rev Peru Med Exp Salud Publica
          Instituto Nacional de Salud (Lima )
          1726-4634
          January 1997
          : 14
          : 1
          : 1
          Article
          S1726-46341997000100001
          10.1056/NEJM197504102921503
          1113797
          e7f5f3d6-7493-435f-a572-3c74df7121ba

          http://creativecommons.org/licenses/by/4.0/

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          Health Policy & Services

          Public health
          Public health

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