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      Safety and feasibility audit of a home-based drug-transitioning approach for patients with pulmonary arterial hypertension: an observational study.

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          Abstract

          Newer endothelin receptor antagonists (ERAs) used to treat patients with pulmonary arterial hypertension (PAH) are associated with fewer drug-drug interactions than bosentan and require less monitoring. This, combined with a pharmacokinetic basis for improved efficacy, means there may be a clinical rationale for changing therapies. However, this can be challenging and few data on its safety in patients with PAH are available.

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          Author and article information

          Journal
          Eur J Cardiovasc Nurs
          European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology
          SAGE Publications
          1873-1953
          1474-5151
          October 2018
          : 17
          : 7
          Affiliations
          [1 ] Royal Free Hospital, London, UK.
          Article
          10.1177/1474515118769534
          29641223
          86e981ed-67f9-4613-88f3-f10c770761c1
          History

          Pulmonary arterial hypertension,endothelin receptor antagonist,transitioning

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