Clozapine-related neutropenia, myocarditis and cardiomyopathy adverse event reports in Australia 1993-2014.

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Abstract

Clozapine is the gold-standard medicine for treating refractory schizophrenia but there are some notable serious adverse events (AE). We aimed to analyse reported rates of clozapine cardiac and haematological AEs in Australia.

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Journal ID (iso-abbrev): Psychopharmacology (Berl.)

Title: Psychopharmacology

Publisher: Springer Nature

ISSN (Electronic): 1432-2072

ISSN (Print): 0033-3158

Publication date (Electronic): Jul 2018

Volume: 235

Issue: 7

Affiliations

[1 ] School of Pharmacy, The University of Queensland, 20 Cornwall St, Woolloongabba, QLD, 4102, Australia. s.hollingworth@uq.edu.au.

[2 ] School of Pharmacy, The University of Queensland, 20 Cornwall St, Woolloongabba, QLD, 4102, Australia.

[3 ] Princess Alexandra Hospital, 199 Ipswich Rd, Woolloongabba, QLD, 4102, Australia.

[4 ] School of Public Health, The University of Queensland, Herston Rd, Herston, QLD, 4006, Australia.

[5 ] Menzies Health Institute Queensland, Meadowbrook, QLD, 4103, Australia.

[6 ] Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, New Zealand.

[7 ] SA Pathology, PO Box 14 Rundle Mall, Adelaide, SA, 5000, Australia.

[8 ] Metro South Addiction and Mental Health Service, 228 Logan Road, Woolloongabba, QLD, 4102, Australia.

[9 ] School of Medicine, The University of Queensland, Herston Rd, Herston, QLD, 4006, Australia.

Article

Publisher Item ID: 10.1007/s00213-018-4881-0

DOI: 10.1007/s00213-018-4881-0

PubMed ID: 29589067

SO-VID: 87141d95-db2e-450e-8142-3255158e0cef

History

Keywords: Pharmacovigilance,Adverse events,Agranulocytosis,Clozapine,Myocarditis cardiomyopathy,Neutropenia

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Keywords: Pharmacovigilance, Adverse events, Agranulocytosis, Clozapine, Myocarditis cardiomyopathy, Neutropenia

Clozapine-related neutropenia, myocarditis and cardiomyopathy adverse event reports in Australia 1993-2014.

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