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      Nanocarriers as an emerging platform for cancer therapy.

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          Abstract

          Nanotechnology has the potential to revolutionize cancer diagnosis and therapy. Advances in protein engineering and materials science have contributed to novel nanoscale targeting approaches that may bring new hope to cancer patients. Several therapeutic nanocarriers have been approved for clinical use. However, to date, there are only a few clinically approved nanocarriers that incorporate molecules to selectively bind and target cancer cells. This review examines some of the approved formulations and discusses the challenges in translating basic research to the clinic. We detail the arsenal of nanocarriers and molecules available for selective tumour targeting, and emphasize the challenges in cancer treatment.

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          Author and article information

          Journal
          Nat Nanotechnol
          Nature nanotechnology
          Springer Science and Business Media LLC
          1748-3395
          1748-3387
          Dec 2007
          : 2
          : 12
          Affiliations
          [1 ] Department of Anesthesia, Immune Disease Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.
          Article
          nnano.2007.387
          10.1038/nnano.2007.387
          18654426
          8721d13c-9e48-4bc4-a3b9-2de49bfb8516
          History

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