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      • Record: found
      • Abstract: found
      • Article: found

      Long-Term Corneal Involvement following Drug-Induced Toxic Epidermal Necrolysis (Lyell’s Disease)

      case-report

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          Abstract

          Toxic epidermal necrolysis is a mucocutaneous disease that also causes important ocular sequelae. Conjunctival retraction, scars and sicca syndrome with severe corneal lesions are the principal ocular complications, sometimes resulting in a major handicap for the patient. We report a case where long-term sequelae ended in corneal perforation requiring a keratoplasty more than 20 years after the initial attack.

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          Author and article information

          Journal
          Journal ID (publisher-id): OPH
          Journal ID (nlm-ta): Ophthalmologica
          Journal ID (doi): 10.1159/issn.0030-3755
          Title: Ophthalmologica
          Publisher: S. Karger AG
          ISSN (Print): 0030-3755
          ISSN (Electronic): 1423-0267
          Publication date Subscription-year: 1993
          Publication date (Print): 1993
          Publication date (Electronic): 01 April 2010
          Volume: 206
          Issue: 3
          Pages: 115-118
          Affiliations
          aServices of Ophthalmology and bDermatology, University of Liège, Belgium
          Article
          Publisher ID: 310375 Other ID: Ophthalmologica 1993;206:115–118
          DOI: 10.1159/000310375
          PubMed ID: 8272332
          SO-VID: 874dc0a7-486f-4b6c-b044-2736c040178b
          Copyright © © 1993 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 21 September 1992
          Date accepted : 24 September 1992
          Page count
          Pages: 4
          Categories
          Subject: Original Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Corneal involvement,Toxic epidermal necrolysis,Lyell’s disease
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Corneal involvement, Toxic epidermal necrolysis, Lyell’s disease

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