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Antitumor Agents, 79. Cytotoxic Antileukemic Alkaloids from Brucea antidysenterica
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Abstract
Two cytotoxic antileukemic alkaloids, the new 1,11-dimethoxycanthin-6-one (3) and
the known 11-hydroxycanthin-6-one (1), as well as the known canthin-6-one (2) were
isolated from the stem of Brucea antidysenterica. The structures of 1-3 were determined
from their spectral data and X-ray analysis of the o-bromobenzoate of 1.