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      Mortality and size of abdominal aortic aneurysm at long-term follow-up of patients not treated surgically and treated with and without statins.

      The American Journal of Cardiology
      Aged, Aortic Aneurysm, Abdominal, drug therapy, mortality, pathology, Female, Heptanoic Acids, therapeutic use, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Male, Pyrroles, Simvastatin

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          Abstract

          Of 130 patients with abdominal aortic aneurysms (AAAs) not treated surgically, 75 (58%) were treated with statins. The sizes of the AAAs were 4.6 +/- 0.6 cm at baseline and 4.5 +/- 0.6 cm at 23-month follow-up in patients treated with statins (p = NS) and 4.5 +/- 0.6 cm at baseline and 5.3 +/- 0.6 cm at 24-month follow-up in patients not treated with statins (p < 0.001). Four of 75 patients (5%) treated with statins died at 45-month follow-up, and 9 of 55 patients (16%) not treated with statins died at 44-month follow-up (p < 0.05).

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