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      Selenium Concentration in Ocular Tissues and Fluids

      research-article
      ,
      Ophthalmic Research
      S. Karger AG
      Iris, Retina, Cornea, Selenium, Aqueous humor, Lens

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          Abstract

          A simple, precise method for the analysis of selenium (Se) in ocular fluids and tissues using electrothermal atomic absorption spectroscopy is presented. Se concentrations ranged from 0.23 to 0.41 μg/g wet weight in the cornea, iris, lens, and retina. The Se concentration in aqueous humor was 0.008 μg/ml, thus much lower than that of plasma (0.21 μg/ml). The concentration of protein in aqueous humor is about 1.0% of plasma. Since in plasma, Se is entirely bound to proteins, it is likely that the difference in Se concentration between plasma and aqueous humor reflects the relative distribution of proteins between these fluids.

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1991
          1991
          10 December 2009
          : 23
          : 1
          : 45-50
          Affiliations
          Department of Anatomy, Physiological Sciences and Radiology, College of Veterinary Medicine, North Carolina State University, Raleigh, N.C., USA
          Article
          267087 Ophthalmic Res 1991;23:45–50
          10.1159/000267087
          1870841
          87eca27c-cf6a-4483-a1c5-720d45ba135b
          © 1991 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 17 April 1990
          : 27 July 1990
          Page count
          Pages: 6
          Categories
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Aqueous humor,Iris,Selenium,Lens,Retina,Cornea
          Vision sciences, Ophthalmology & Optometry, Pathology
          Aqueous humor, Iris, Selenium, Lens, Retina, Cornea

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