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      A cisplatin plus pirarubicin-based JPLT2 chemotherapy for hepatoblastoma: experience and future of the Japanese Study Group for Pediatric Liver Tumor (JPLT).

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          Abstract

          The Japanese Study Group for Pediatric Liver Tumor (JPLT) has conducted cooperative treatment studies on hepatoblastoma (HBL) since 1991. The JPLT2 protocol was launched in 1999 to evaluate the efficacy of cisplatin/pirarubicin (CITA) under risk stratification. European and North American groups showed the improvement of HBL patients by pre- and postoperative chemotherapeutic regimens. Therefore, we evaluated the results of JPLT study and considered the future aspect of JPLT.

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          Author and article information

          Journal
          Pediatr. Surg. Int.
          Pediatric surgery international
          Springer Nature America, Inc
          1437-9813
          0179-0358
          Oct 2013
          : 29
          : 10
          Affiliations
          [1 ] Department of Pediatric Surgery, Hiroshima University Hospital, Hiroshima, Japan, eiso@hiroshima-u.ac.jp.
          Article
          10.1007/s00383-013-3399-0
          24026876
          881ba33d-53c6-4057-80a5-f052a5f86a0a
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