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      Clock mutants of Drosophila melanogaster.

      Proceedings of the National Academy of Sciences of the United States of America

      Temperature, Sex Chromosomes, Recombination, Genetic, Phenotype, Mutation, Male, Locomotion, Genotype, Genetic Linkage, Genes, Female, Drosophila melanogaster, Circadian Rhythm, Chromosome Mapping, Animals

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          Abstract

          Three mutants have been isolated in which the normal 24-hour rhythm is drastically changed. One mutant is arrhythmic; another has a period of 19 hr; a third has a period of 28 hr. Both the eclosion rhythm of a population and the locomotor activity of individual flies are affected. All these mutations appear to involve the same functional gene on the X chromosome.

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          Journal
          389363
          5002428

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