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      Plasma Renin Concentration and the Control of Blood Pressure in Patients on Maintenance Haemodialysis

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      Nephron

      S. Karger AG

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          Abstract

          Plasma renin concentration was measured in 19 patients undergoing maintenance haemodialysis for chronic renal failure. The highest plasma renin concentrations were found in the two patients in whom bilateral nephrectomy was necessary to control blood pressure. Normal or moderately raised renin values were found in the remaining patients in whom blood pressure was more readily controlled. Bilateral nephrectomy reduced plasma renin concentration in each of 6 patients, although renin-like activity did not disappear from blood in the months following the operation. Marked loss of weight during dialysis increased plasma renin concentration whereas lesser reduction in weight usually produced a fall in plasma renin concentration.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          978-3-8055-0996-1
          978-3-318-02134-9
          1660-8151
          2235-3186
          1969
          1969
          26 November 2008
          : 6
          : 3
          : 329-349
          Affiliations
          M.R.C. Blood Pressure Research Unit, Western Infirmary, Glasgow and Department of Medicine, Charing Cross Hospital Medical School, Fulham Hospital, London
          Article
          179737 Nephron 1969;6:329–349
          10.1159/000179737
          5791281
          © 1969 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 21
          Categories
          Paper

          Cardiovascular Medicine, Nephrology

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