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      Theta oscillations in the hippocampus.

      1
      Neuron
      Elsevier BV

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          Abstract

          Theta oscillations represent the "on-line" state of the hippocampus. The extracellular currents underlying theta waves are generated mainly by the entorhinal input, CA3 (Schaffer) collaterals, and voltage-dependent Ca(2+) currents in pyramidal cell dendrites. The rhythm is believed to be critical for temporal coding/decoding of active neuronal ensembles and the modification of synaptic weights. Nevertheless, numerous critical issues regarding both the generation of theta oscillations and their functional significance remain challenges for future research.

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          Author and article information

          Journal
          Neuron
          Neuron
          Elsevier BV
          0896-6273
          0896-6273
          Jan 31 2002
          : 33
          : 3
          Affiliations
          [1 ] Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey and Neurological Institute of New Jersey, Newark, NJ 07102, USA. buzsaki@axon.rutgers.edu
          Article
          S089662730200586X
          10.1016/s0896-6273(02)00586-x
          11832222
          8857bbe9-ed95-4cbc-a44c-a070cf727c99

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