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      BioDB extractor: customized data extraction system for commonly used bioinformatics databases

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          Abstract

          Background

          Diverse types of biological data, primary as well as derived, are available in various formats and are stored in heterogeneous resources. Database-specific as well as integrated search engines are available for carrying out efficient searches of databases. These search engines however, do not support extraction of subsets of data with the same level of granularity that exists in typical database entries. In order to extract fine grained subsets of data, users are required to download complete or partial database entries and write scripts for parsing and extraction.

          Results

          BioDBExtractor (BDE) has been developed to provide 26 customized data extraction utilities for some of the commonly used databases such as ENA (EMBL-Bank), UniprotKB, PDB, and KEGG. BDE eliminates the need for downloading entries and writing scripts. BDE has a simple web interface that enables input of query in the form of accession numbers/ID codes, choice of utilities and selection of fields/subfields of data by the users.

          Conclusions

          BDE thus provides a common data extraction platform for multiple databases and is useful to both, novice and expert users. BDE, however, is not a substitute to basic keyword-based database searches. Desired subsets of data, compiled using BDE can be subsequently used for downstream processing, analyses and knowledge discovery.

          Availability

          BDE can be accessed from http://bioinfo.net.in/BioDB/Home.html.

          Related collections

          Most cited references25

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          Reorganizing the protein space at the Universal Protein Resource (UniProt)

          The mission of UniProt is to support biological research by providing a freely accessible, stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive cross-references and querying interfaces. UniProt is comprised of four major components, each optimized for different uses: the UniProt Archive, the UniProt Knowledgebase, the UniProt Reference Clusters and the UniProt Metagenomic and Environmental Sequence Database. A key development at UniProt is the provision of complete, reference and representative proteomes. UniProt is updated and distributed every 4 weeks and can be accessed online for searches or download at http://www.uniprot.org.
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            DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions.

            I Xenarios (2002)
            The Database of Interacting Proteins (DIP: http://dip.doe-mbi.ucla.edu) is a database that documents experimentally determined protein-protein interactions. It provides the scientific community with an integrated set of tools for browsing and extracting information about protein interaction networks. As of September 2001, the DIP catalogs approximately 11 000 unique interactions among 5900 proteins from >80 organisms; the vast majority from yeast, Helicobacter pylori and human. Tools have been developed that allow users to analyze, visualize and integrate their own experimental data with the information about protein-protein interactions available in the DIP database.
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              • Record: found
              • Abstract: found
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              The IntAct molecular interaction database in 2012

              IntAct is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. Two levels of curation are now available within the database, with both IMEx-level annotation and less detailed MIMIx-compatible entries currently supported. As from September 2011, IntAct contains approximately 275 000 curated binary interaction evidences from over 5000 publications. The IntAct website has been improved to enhance the search process and in particular the graphical display of the results. New data download formats are also available, which will facilitate the inclusion of IntAct's data in the Semantic Web. IntAct is an active contributor to the IMEx consortium (http://www.imexconsortium.org). IntAct source code and data are freely available at http://www.ebi.ac.uk/intact.
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                Author and article information

                Contributors
                rajiv@bioinfo.net.in , rajivkarbhal@gmail.com
                +91 20 2569 0195 , sangeeta@bioinfo.net.in , sawantsangeeta@gmail.com
                urmila@bioinfo.net.in , urmila.kulkarni.kale@gmail.com
                Journal
                BioData Min
                BioData Min
                BioData Mining
                BioMed Central (London )
                1756-0381
                28 October 2015
                28 October 2015
                2015
                : 8
                : 31
                Affiliations
                Bioinformatics Centre, Savitribai Phule Pune University, Ganeshkhind, Pune, 411007 Maharashtra India
                Article
                67
                10.1186/s13040-015-0067-z
                4624652
                26516349
                8871efbb-1f7c-4242-b9cb-f39d63d6245c
                © Karbhal et al. 2015

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 19 March 2015
                : 20 October 2015
                Categories
                Research
                Custom metadata
                © The Author(s) 2015

                Bioinformatics & Computational biology
                bioinformatics,biological databases,customized data retrieval,data integration,database cross-linking

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