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Statin therapy reduces plasma endothelin-1 concentrations: A meta-analysis of 15 randomized controlled trials
Amirhossein Sahebkar ,
Kazuhiko Kotani ,
Corina Serban ,
Sorin Ursoniu ,
Dimitri P. Mikhailidis ,
Steven R. Jones ,
Kausik K. Ray ,
Michael J. Blaha ,
Jacek Rysz ,
Peter P. Toth ,
Paul Muntner ,
Gregory Y.H. Lip ,
Maciej Banach
August 2015
August 2015
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Abstract
Raised plasma endothelin-1 (ET-1) levels may be a risk factor for vascular dysfunction
and cardiovascular (CV) disease. This meta-analysis assessed the effect of statins
on circulating ET-1 concentrations.
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