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      Cancer Therapy: Anti‐Metastatic and Anti‐Angiogenic Activities of Core–Shell SiO 2@LDH Loaded with Etoposide in Non‐Small Cell Lung Cancer (Adv. Sci. 11/2016)

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          Abstract

          In article 1600229, Shilong Wang, Rongrong Zhu, Yechang Qian, and co‐workers investigate the anti‐metastatic and anti‐angiogenic effects of SiO 2@LDH (LDH: layered double hydroxide) loaded with etoposide (VP16). SiO 2@LDH has very suitable qualities as drug delivery agent and enhances the anti‐metastatic action of VP16 both in vitro and in vivo. Enhanced anti‐angiogenic efficacy is also proven which might contribute to the anti‐cancer action. The cover image represents the 3D structure of core‐shell SiO 2@LDH‐VP16, which silicon dioxide sphere flexibly enclosed by double‐layered hydroxide.

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          Author and article information

          Journal
          Adv Sci (Weinh)
          Adv Sci (Weinh)
          10.1002/(ISSN)2198-3844
          ADVS
          Advanced Science
          John Wiley and Sons Inc. (Hoboken )
          2198-3844
          09 November 2016
          November 2016
          : 3
          : 11 ( doiID: 10.1002/advs.v3.11 )
          : n/a
          Affiliations
          [ 1 ] Research Center for Translational Medicine at East Hospital School of Life Science and TechnologyTongji University Shanghai 200092China
          [ 2 ] Department of Respiratory DiseaseBaoshan District Hospital of Integrated Traditional Chinese and Western Medicine Shanghai 201900China
          Article
          ADVS201670056
          10.1002/advs.201670056
          5115527
          8a38df6f-3dc6-4c54-8b6f-2470870ceb87
          © 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

          This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

          History
          Page count
          Figures: 1, Tables: 0, Pages: 1, Words: 238
          Categories
          Cover Picture
          Cover Picture
          Custom metadata
          2.0
          advs201670056
          November 2016
          Converter:WILEY_ML3GV2_TO_NLMPMC version:4.9.8 mode:remove_FC converted:18.11.2016

          anti‐angiogenic,anti‐metastasis,etoposide,lung cancer,sio2@ldh

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