Autophagy in Hepatocytes in Infants With Alpha-1 ATD and Different Liver Disease Outcomes: A Retrospective Analysis.

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Abstract

It is unclear whether a distinct activity of pathways removing the antitrypsin (AT) protein in Alpha-1-Antitrypsin Deficiency (α1ATD) are associated with an unfavorable predisposition to liver disease in the future. The aim of this study was to determine whether liverspecific activity of AT protein disposal occurs at infancy in α1ATD with PiZZ phenotype (ATZ).

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Author and article information

Journal

Journal ID (iso-abbrev): J. Pediatr. Gastroenterol. Nutr.

Title: Journal of pediatric gastroenterology and nutrition

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1536-4801

ISSN (Print): 0277-2116

Publication date (Electronic): Jun 2017

Volume: 64

Issue: 6

Affiliations

[1 ] *Department of Pathology †Department of Gastroenterology, Hepatology Nutrition Disorders and Paediatrics, The Children's Memorial Health Institute ‡Department of Histology and Embryology, Medical University of Warsaw, Warsaw, Poland.

Article

DOI: 10.1097/MPG.0000000000001507

PubMed ID: 28045767

SO-VID: 8a7829a9-b40f-47a4-9901-24594cba9306

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