+1 Recommend
2 collections
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Dermatitis linearis outbreak associated with Paederus balcanicus in Austria


      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.



          Dermatitis linearis is a toxic skin lesion caused by contact with certain beetles of the genus Paederus (Coleoptera: Staphylinidae). Dermatitis linearis outbreaks have been described mainly in tropical and subtropical regions, but so far not in Central Europe, and are considered an emerging public health concern potentially associated with climate change.

          Material and methods

          Following diagnosis of dermatitis linearis in a cluster of six adults and one child with reported exposure to beetles with morphological characteristics of Paederus species at a recreational public open-air bath at Lake Neusiedl (Illmitz, Burgenland, Austria), we performed on-site inspection and installed light and pitfall traps. Collected beetle specimens of the genus Paederus were classified using morphological characteristics and DNA barcoding.


          A total of 32  Paederus beetles were collected using an aspirator ( n = 2) and light traps ( n = 30). No individuals of the genus Paederus were captured with the pitfall traps. Morphological analyses identified them as members of the Paederus balcanicus species, which was confirmed by genetic specification of four arbitrarily chosen individuals. Dermatitis linearis lesions were treated with topical steroids and healed but partly leaving scars and hyperpigmentation, over the course of a few weeks in all affected persons.


          We report for the first time (a) an outbreak of dermatitis linearis associated with exposure to autochthonous Paederus species in Austria, and (b) that contact to the species Paederus balcanicus may cause dermatitis linearis in humans. Adequate measures should be taken to prevent dermatitis linearis outbreaks in areas with resident Paederus occurrence.

          Related collections

          Most cited references16

          • Record: found
          • Abstract: found
          • Article: not found

          DNA primers for amplification of mitochondrial cytochrome c oxidase subunit I from diverse metazoan invertebrates.

          M Beier (1966)
          We describe "universal" DNA primers for polymerase chain reaction (PCR) amplification of a 710-bp fragment of the mitochondrial cytochrome c oxidase subunit I gene (COI) from 11 invertebrate phyla: Echinodermata, Mollusca, Annelida, Pogonophora, Arthropoda, Nemertinea, Echiura, Sipuncula, Platyhelminthes, Tardigrada, and Coelenterata, as well as the putative phylum Vestimentifera. Preliminary comparisons revealed that these COI primers generate informative sequences for phylogenetic analyses at the species and higher taxonomic levels.
            • Record: found
            • Abstract: not found
            • Article: not found

            Differential efficacy of toxic pederin in deterring potential arthropod predators of Paederus (Coleoptera: Staphylinidae) offspring

              • Record: found
              • Abstract: found
              • Article: not found

              Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs.

              The potent cytotoxins pederin and psymberin have been prepared through concise synthetic routes (10 and 14 steps in the longest linear sequences, respectively) that proceed via a late-stage multicomponent approach to construct the N-acyl aminal linkages. This route allowed for the facile preparation of a number of analogs that were designed to explore the importance of the alkoxy group in the N-acyl aminal and functional groups in the two major subunits on biological activity. These analogs, including a pederin/psymberin chimera, were analyzed for their growth inhibitory effects, revealing several new potent cytotoxins and leading to postulates regarding the molecular conformational and hydrogen bonding patterns that are required for biological activity. Second generation analogs have been prepared based on the results of the initial assays and a structure-based model for the binding of these compounds to the ribosome. The growth inhibitory properties of these compounds are reported. These studies show the profound role that organic chemistry in general and specifically late-stage multicomponent reactions can play in the development of unique and potent effectors for biological responses.

                Author and article information

                Wien Klin Wochenschr
                Wien Klin Wochenschr
                Wiener Klinische Wochenschrift
                Springer Vienna (Vienna )
                20 June 2022
                20 June 2022
                : 134
                : 13-14
                : 511-515
                [1 ]GRID grid.414107.7, ISNI 0000 0001 2224 6253, Institute for Medical Microbiology and Hygiene, , Austrian Agency for Health and Food Safety (AGES), ; Währingerstr. 25A, 1090 Vienna, Austria
                [2 ]Palais Kinsky, Freyung 4/17, 1010 Vienna, Austria
                [3 ]GRID grid.6583.8, ISNI 0000 0000 9686 6466, Institute of Parasitology, , University of Veterinary Medicine Vienna, ; Vienna, Austria
                [4 ]GRID grid.22937.3d, ISNI 0000 0000 9259 8492, Center for Cancer Research, , Medical University of Vienna, ; Vienna, Austria
                [5 ]GRID grid.511716.5, ISNI 0000 0004 0521 4278, Biological Station Lake Neusiedl, ; Illmitz, Austria
                [6 ]GRID grid.22937.3d, ISNI 0000 0000 9259 8492, Division of Oncology, Department of Medicine I, , Medical University of Vienna, ; Vienna, Austria
                Author information
                © The Author(s) 2022

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                : 28 August 2021
                : 19 May 2022
                Funded by: Medical University of Vienna
                Short Report
                Custom metadata
                © Springer-Verlag GmbH Austria, part of Springer Nature 2022

                paederus balcanicus,rove beetle,staphylinidae,exanthema,lake neusiedl
                paederus balcanicus, rove beetle, staphylinidae, exanthema, lake neusiedl


                Comment on this article