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      Novel gene targets for miRNA146a and miRNA155 in anterior uveitis.

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          Abstract

          Anterior uveitis (AU) is the most common form of intraocular inflammation. MicroRNAs (miRNA) are small, non-coding RNAs functioning as post-transcriptional repressors of gene expression. Knowledge of miRNAs can implicate specific genes and pathogenic signalling pathways in disease. This study examines miRNA expression, function and target genes in AU pathogenesis.

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          Author and article information

          Journal
          Br J Ophthalmol
          The British journal of ophthalmology
          BMJ
          1468-2079
          0007-1161
          February 2019
          : 103
          : 2
          Affiliations
          [1 ] Department of Ophthalmology, Royal College of Surgeons in Ireland, Royal Victoria Eye and Ear Hospital, Dublin, Ireland maorourk@tcd.ie.
          [2 ] Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital, University College, Dublin, Ireland.
          [3 ] Molecular Rheumatology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland.
          [4 ] Department of Ophthalmology, Royal College of Surgeons in Ireland, Royal Victoria Eye and Ear Hospital, Dublin, Ireland.
          Article
          bjophthalmol-2018-312885
          10.1136/bjophthalmol-2018-312885
          30297336
          8aaa20df-36bd-4446-92fd-7453a2a66d9a
          © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
          History

          experimental-laboratory,genetics,immunology,inflammation

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