Journal ID (nlm-journal-id): 0410462
Journal ID (pubmed-jr-id): 6011
Journal ID (nlm-ta): Nature
Title:
Nature
ISSN
(Print):
0028-0836
ISSN
(Electronic):
1476-4687
Publication date Nihms-submitted: 28
December
2009
Publication date
(Print):
4
March
2010
Publication date PMC-release: 4
September
2010
Volume: 464
Issue: 7285
Pages: 121-125
Affiliations
[1
]
Gladstone Institute of Virology and Immunology, University of California San Francisco,
CA
[2
]
Department of Medicine, University of California, San Francisco
[3
]
Department of Pediatrics, The Children’s Hospital of Pittsburgh, University of Pittsburgh
School of Medicine, Pittsburgh, PA
[4
]
Joslin Diabetes Center, Harvard Medical School, Boston, MA
[5
]
Howard Hughes Medical Institute, The Children’s Hospital, Department of Genetics,
Harvard Medical School, Boston, MA
[6
]
Gladstone Institute of Cardiovascular Disease, University of California San Francisco,
CA
[7
]
Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center,
Durham NC
[8
]
Cell Signaling Technology, Danvers, MA
[9
]
Department of Medicine, Physiology, and Biophysics and the Diabetes Unit, Boston University
Medical Center, Boston, MA
Author notes
Author Contributions MH, TS, EG, EJ, CG, CH, SB, and AS performed
in vitro, in vivo and biochemical studies; OI, RS, JB performed metabolomic studies; BS, DL, and YL
carried out mass spectrometry studies; MH and EV designed the studies, analyzed the
data, and wrote the manuscript; all other authors reviewed and commented on the manuscript.
Article
Manuscript ID: nihpa166711
DOI: 10.1038/nature08778
PMC ID: 2841477
PubMed ID: 20203611
SO-VID: 8ac37bde-95bb-45e8-b6ac-6d65f4903a8d
License:
Users may view, print, copy, download and text and data- mine the content in such
documents, for the purposes of academic research, subject always to the full Conditions
of use:
http://www.nature.com/authors/editorial_policies/license.html#terms
Funded by: National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK
Funded by: National Heart, Lung, and Blood Institute : NHLBI
Funded by: National Institute on Aging : NIA
Funded by: Howard Hughes Medical Institute
Award ID: U24 DK059637-01
||DK
Funded by: National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK
Funded by: National Heart, Lung, and Blood Institute : NHLBI
Funded by: National Institute on Aging : NIA
Funded by: Howard Hughes Medical Institute
Award ID: R01 DK067509-04
||DK
Funded by: National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK
Funded by: National Heart, Lung, and Blood Institute : NHLBI
Funded by: National Institute on Aging : NIA
Funded by: Howard Hughes Medical Institute
Award ID: R01 DK019514-29
||DK
Funded by: National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK
Funded by: National Heart, Lung, and Blood Institute : NHLBI
Funded by: National Institute on Aging : NIA
Funded by: Howard Hughes Medical Institute
Award ID: P30 DK026743-26A1
||DK
Funded by: National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK
Funded by: National Heart, Lung, and Blood Institute : NHLBI
Funded by: National Institute on Aging : NIA
Funded by: Howard Hughes Medical Institute
Award ID: P01 HL068758-06A1
||HL
Funded by: National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK
Funded by: National Heart, Lung, and Blood Institute : NHLBI
Funded by: National Institute on Aging : NIA
Funded by: Howard Hughes Medical Institute
Award ID: K08 AG022325-01A1
||AG
Funded by: National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK
Funded by: National Heart, Lung, and Blood Institute : NHLBI
Funded by: National Institute on Aging : NIA
Funded by: Howard Hughes Medical Institute
Award ID:
||HHMI_