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      International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial.

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          Abstract

          Endovascular detachable coil treatment is being increasingly used as an alternative to craniotomy and clipping for some ruptured intracranial aneurysms, although the relative benefits of these two approaches have yet to be established. We undertook a randomised, multicentre trial to compare the safety and efficacy of endovascular coiling with standard neurosurgical clipping for such aneurysms judged to be suitable for both treatments.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          0140-6736
          0140-6736
          Oct 26 2002
          : 360
          : 9342
          Affiliations
          [1 ] ISAT, Neurovascular Research Unit, Radcliffe Infirmary, Oxford OX2 6HE, UK. isat@radiology.ox.ac.uk
          Article
          S0140673602113146
          10.1016/s0140-6736(02)11314-6
          12414200
          8ad987b1-f60e-49dd-b14a-3d1453296729
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