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      Microbial metabolism. Part 13. Metabolites of hesperetin.

      Bioorganic & Medicinal Chemistry Letters

      Antineoplastic Agents, chemistry, isolation & purification, metabolism, pharmacology, Antioxidants, Drug Screening Assays, Antitumor, Fermentation, Flavanones, Hesperidin, Molecular Structure, Mucor

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          Abstract

          The fungal culture, Mucor ramannianus (ATCC 2628) transformed hesperitin (1) to four metabolites: 4'-methoxy-5,7,8,3'-tetrahydroxyflavanone (8-hydroxyhesperetin) (2), 5,7,3',4'-tetrahydroxyflavanone (eriodictyol) (3), 4'-methoxy-5,3'-dihydroxyflavanone 7-sulfate (hesperetin 7-sulfate) (4) and 5,7,3'-trihydroxyflavanone 4'-O-α-quinovopyranoside (eriodictyol 4'-O-α-quinovopyranoside) (5). The structures were established by spectroscopic methods. Copyright © 2011 Elsevier Ltd. All rights reserved.

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          Journal
          21873058
          10.1016/j.bmcl.2011.08.004

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