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      Comparative effectiveness of mepolizumab and omalizumab in severe asthma: An indirect treatment comparison.

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          Abstract

          Severe asthma is a heterogeneous disease. Patients with both eosinophilic and allergic asthma phenotypes may be eligible for treatment with mepolizumab and omalizumab. Evidence on the relative effectiveness of these treatments in this 'overlap' population would be informative for clinical and payer decision making.

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          Author and article information

          Journal
          Respir Med
          Respiratory medicine
          Elsevier BV
          1532-3064
          0954-6111
          Feb 2017
          : 123
          Affiliations
          [1 ] Value Evidence and Outcomes, GSK, GSK House, Brentford, Middlesex, UK.
          [2 ] Clinical Statistics, GSK, Stockley Park, Uxbridge, UK.
          [3 ] Value Evidence Analytics, GSK, Philadelphia, PA, USA.
          [4 ] Global Market Access Solutions, Health Economics and Outcomes Research, London, UK.
          [5 ] Respiratory Therapeutic Area, GSK, Research Triangle Park, NC, USA.
          [6 ] Value Evidence and Outcomes, GSK, GSK House, Brentford, Middlesex, UK. Electronic address: jenny.x.willson@gsk.com.
          Article
          S0954-6111(16)30337-7
          10.1016/j.rmed.2016.12.009
          28137490
          8b29b13f-343f-47ab-9938-883b626c1653
          History

          Exacerbations,Lung function,Mepolizumab,Omalizumab,Severe asthma,Tolerability

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