Implication of osteoprotegerin and sclerostin in axial spondyloarthritis cardiovascular disease: study of 163 Spanish patients.

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Abstract

Due to the high incidence of cardiovascular disease in axial spondyloarthritis (axSpA), the search of potential biomarkers that may help to identify patients with high cardiovascular risk is of main importance. Therefore, in this study we assessed the implication of osteoprotegerin (OPG) and sclerostin (SCL), two biomarkers associated with cardiovascular disease and bone metabolism, in the clinical spectrum and atherosclerotic disease of patients with axSpA.

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Journal

Journal ID (iso-abbrev): Clin. Exp. Rheumatol.

Title: Clinical and experimental rheumatology

ISSN: 0392-856X

ISSN (Print): 0392-856X

Publication date (Electronic): January 6 2018

Volume: 36

Issue: 2

Affiliations

[1 ] Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain.

[2 ] Bone Metabolism Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, RETICEF, Santander, Spain.

[3 ] Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain.

[4 ] Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain. rlopezmejias78@gmail.com.

[5 ] Epidemiol., Genetics, Atherosclerosis Res. Group on Systemic Inflamm. Diseases, IDIVAL; School of Medicine, Univ. of Cantabria, Santander, Spain; Cardiovascular Pathophysiol. & Genomics Res. Unit, Faculty of Health Sciences, Univ. Witwatersrand, S.Africa.

Article

Publisher Item ID: 11893

PubMed ID: 29303699

SO-VID: 8b3287ce-e5fc-49c7-b425-9efdbd1cdbfe

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