Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation: results on health-related quality of life and symptom burden. The MANTRA-PAF trial.

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Abstract

The Medical ANtiarrhythmic Treatment or Radiofrequency Ablation in Paroxysmal Atrial Fibrillation (MANTRA-PAF) trial assessed the long-term efficacy of an initial strategy of radiofrequency ablation (RFA) vs. antiarrhythmic drug therapy (AAD) as first-line treatment for patients with PAF. In this substudy, we evaluated the effect of these treatment modalities on the Health-Related Quality of Life (HRQoL) and symptom burden of patients at 12 and 24 months.

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Journal ID (iso-abbrev): Europace

Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

ISSN (Electronic): 1532-2092

ISSN (Print): 1099-5129

Publication date (Electronic): Feb 2015

Volume: 17

Issue: 2

Affiliations

[1 ] Department of Cardiology and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden hakan.walfridsson@lio.se.

[2 ] Division of Nursing Science, Department of Medical and Health Sciences, Linkoping University, Linkoping, Sweden.

[3 ] Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

[4 ] Gentofte University Hospital, Copenhagen, Denmark.

[5 ] Heart Center Co. Tampere University Hospital, Tampere, Finland.

[6 ] Department of Cardiology and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.

[7 ] Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.

[8 ] Leipzig University Hospital, Leipzig, Germany.

[9 ] Lund University Hospital, Sweden.

[10 ] Rigshospitalet, Copenhagen, Denmark.

[11 ] University Hospital, Örebro, Sweden.

[12 ] Kuopio University Hospital, Kuopio, Finland.

[13 ] UNI-C, Danish Information Technology Centre for Education and Research, Aarhus, Denmark.

Article

Publisher Item ID: euu342

DOI: 10.1093/europace/euu342

PubMed ID: 25567068

SO-VID: 8b699d49-7e82-4e75-84e8-ebffb2cd9717

History

Keywords: Antiarrhythmic drug treatment,Atrial fibrillation,Catheter ablation,First-line therapy,Quality of life

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Keywords: Antiarrhythmic drug treatment, Atrial fibrillation, Catheter ablation, First-line therapy, Quality of life

Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation: results on health-related quality of life and symptom burden. The MANTRA-PAF trial.

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Asian Journal of Quality of Life (AjQoL)

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