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      Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies.

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          Abstract

          Understanding the relationship between aneuploidy detection on noninvasive prenatal testing (NIPT) and occult maternal malignancies may explain results that are discordant with the fetal karyotype and improve maternal clinical care.

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          Author and article information

          Journal
          JAMA
          JAMA
          1538-3598
          0098-7484
          Jul 14 2015
          : 314
          : 2
          Affiliations
          [1 ] Mother Infant Research Institute, Tufts Medical Center, Boston, Massachusetts.
          [2 ] Illumina, Redwood City, California.
          [3 ] Center for Genetics and Maternal Fetal Medicine, Springfield, Oregon.
          [4 ] Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Minnesota, Minneapolis.
          [5 ] Dana-Farber Cancer Institute, Boston, Massachusetts.
          [6 ] Division of Maternal Fetal Medicine and Reproductive Genetics, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.
          [7 ] University of North Carolina, Chapel Hill.
          [8 ] Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk.
          [9 ] San Francisco Perinatal Associates, San Francisco, California.
          [10 ] Sharp Rees-Stealy Medical Group, San Diego, California.
          Article
          2389341
          10.1001/jama.2015.7120
          26168314
          8ba8e7bf-a3ed-494e-a4f8-d348904d1ca0
          History

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