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      Geroscience in the Age of COVID-19

      editorial

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          Abstract

          The data on COVID-19 is clear on at least one point: Older adults are most vulnerable to hospitalization, disability and death following infection with the novel coronavirus. Therefore, therapeutically addressing degenerative aging processes as the main risk factors appears promising for tackling the present crisis and is expected to be relevant when tackling future infections, epidemics and pandemics. Therefore, utilizing a geroscience approach, targeting aging processes to prevent multimorbidity, via initiating broad clinical trials of potential geroprotective therapies, is recommended.

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          Most cited references18

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          Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

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            Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

            There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19).
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              Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis

              Highlights • COVID -19 cases are now confirmed in multiple countries. • Assessed the prevalence of comorbidities in infected patients. • Comorbidities are risk factors for severe compared with non-severe patients. • Help the health sector guide vulnerable populations and assess the risk of deterioration.
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                Author and article information

                Journal
                Aging Dis
                Aging Dis
                Aging and Disease
                JKL International LLC
                2152-5250
                July 2020
                23 July 2020
                : 11
                : 4
                : 725-729
                Affiliations
                [1-ad-11-4-725] 1Institute for Aging Research, Albert Einstein College of Medicine, New York, NY, USA
                [2-ad-11-4-725] 2Gerontological Society of America, USA
                [3-ad-11-4-725] 3Department of Biology, University of Alabama at Birmingham, USA
                [4-ad-11-4-725] 4Department of Pathology, University of Washington, USA
                [5-ad-11-4-725] 5Geroscience Center for Brain Health and Metabolism (GERO), Chile
                [6-ad-11-4-725] 6The Buck Institute for Research on Aging, USA
                [7-ad-11-4-725] 7American Federation for Aging Research, USA
                [8-ad-11-4-725] 8Vetek (Seniority) Association - the Movement for Longevity and Quality of Life, Israel
                [9-ad-11-4-725] 9National Institute on Aging, NIH, USA
                Author notes
                [* ]Correspondence should be addressed to: Dr. Nir Barzilai, Albert Einstein College of Medicine, New York, NY, USA. Email: nir.barzilai@ 123456einsteinmed.org . Dr. Ilia Stambler, Vetek (Seniority) Association - the Movement for Longevity and Quality of Life, Israel. Email: ilia.stambler@ 123456gmail.com . Dr. Felipe Sierra, National Institute on Aging, NIH, USA. Email: sierraf@ 123456nia.nih.gov .
                Article
                ad-11-4-725
                10.14336/AD.2020.0629
                7390533
                32765937
                8bfadaa4-3f36-4a5c-bb7b-038eb0e90b9b
                Copyright: © 2020 Barzilai et al.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

                History
                : 20 June 2020
                : 28 June 2020
                : 29 June 2020
                Categories
                Editorial

                geroscience,covid-19,immunosenescence,geroprotectors,aging biomarkers

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