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      Brachytherapy in cervical cancer radiotherapy during COVID-19 pandemic crisis: problems and prospects

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          Abstract

          COVID-19 pandemic has adversely affected general healthcare delivery systems and cancer care throughout the world. The management of locally advanced cervical cancer presents specific challenges in this context, especially brachytherapy and completion of radiotherapy treatment, without compromising the overall treatment time and anticipated outcomes. This article presents in detail the issues and possible solutions with currently available literature for COVID-19 and radiation, in particular brachytherapy management of locally advanced cervical cancers. The review attempts to provide possible explanations and pathways based on COVID-19 testing, brachytherapy processes including application, imaging, and fractionation, keeping in mind the overall treatment time.

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          Most cited references 10

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          Effect of tumor dose, volume and overall treatment time on local control after radiochemotherapy including MRI guided brachytherapy of locally advanced cervical cancer.

          Currently, there is no consensus on dose prescription in image guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer. The purpose of this study was to provide evidence based recommendations for tumor dose prescription based on results from a multi-center patient series (retroEMBRACE).
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            COVID-19 Global Pandemic: Options for Management of Gynecologic Cancers

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              Template-based high-dose-rate interstitial brachytherapy in gynecologic cancers: a single institutional experience.

              To report the outcome and toxicities of radical external beam radiotherapy (EBRT) and template-based high-dose-rate interstitial brachytherapy (ISBT) in patients diagnosed with cervical cancer undergoing inadvertent surgery, vault cancers, and vaginal cancers at our institution.
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                Author and article information

                Journal
                J Contemp Brachytherapy
                J Contemp Brachytherapy
                JCB
                Journal of Contemporary Brachytherapy
                Termedia Publishing House
                1689-832X
                2081-2841
                30 June 2020
                June 2020
                : 12
                : 3
                : 290-293
                Affiliations
                Department of Radiation Oncology, Homi Bhabha Cancer Hospital and Research Centre, Visakhapatnam, Andhra Pradesh, India
                Author notes
                Address for correspondence: Umesh Mahantshetty, MD, DNB, Director and Professor, Radiation Oncology, Homi Bhabha Cancer Hospital and Research Centre (a unit of Tata Memorial Centre), Visakhapatnam, Andhra Pradesh – 530053, India, e-mail: drumeshm@ 123456gmail.com
                Article
                41160
                10.5114/jcb.2020.96873
                7366013
                Copyright © 2020 Termedia

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License ( http://creativecommons.org/licenses/by-nc-sa/4.0/)

                Categories
                Original Paper

                Oncology & Radiotherapy

                hdr fractionation, brachytherapy, cervical cancer radiotherapy, covid-19

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