Lung-Protective Ventilation With Low Tidal Volumes and the Occurrence of Pulmonary Complications in Patients Without Acute Respiratory Distress Syndrome: A Systematic Review and Individual Patient Data Analysis.

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Abstract

Protective mechanical ventilation with low tidal volumes is standard of care for patients with acute respiratory distress syndrome. The aim of this individual patient data analysis was to determine the association between tidal volume and the occurrence of pulmonary complications in ICU patients without acute respiratory distress syndrome and the association between occurrence of pulmonary complications and outcome in these patients.

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Journal

Journal ID (iso-abbrev): Crit. Care Med.

Title: Critical care medicine

ISSN (Electronic): 1530-0293

ISSN (Print): 0090-3493

Publication date (Electronic): Oct 2015

Volume: 43

Issue: 10

Affiliations

[1 ] 1Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. 2Program of Post-Graduation, Research and Innovation, Faculdade de Medicina do ABC (FMABC), Santo André, Brazil. 3Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil. 4Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN. 5Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA. 6School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. 7Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Peijas Hospital, Vantaa, Finland. 8Medical School, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil. 9Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA. 10Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. 11Department of Surgical Sciences and Integrated Diagnostics, IRCCS San Martino IST, University of Genoa, Genoa, Italy. 12Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Article

DOI: 10.1097/CCM.0000000000001189

PubMed ID: 26181219

SO-VID: 8ca5e0e2-338d-46cf-828c-199f1212c82e

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