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      Imported Case of Poliomyelitis, Melbourne, Australia, 2007

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          Abstract

          Wild poliovirus–associated paralytic poliomyelitis has not been reported in Australia since 1977. We report type 1 wild poliovirus infection in a man who had traveled from Pakistan to Australia in 2007. Poliomyelitis should be considered for patients with acute flaccid paralysis or unexplained fever who have been to poliomyelitis-endemic countries.

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          Most cited references8

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          General primer-mediated polymerase chain reaction for detection of enteroviruses: application for diagnostic routine and persistent infections.

          The aim of this study was to determine the applicability of the polymerase chain reaction (PCR) for routine diagnostic use and for the detection of persistent enteroviral infections. To this end, general primers were selected in the highly conserved part of the 5'-noncoding region of the enteroviral genome. They were tested on 66 different enterovirus serotypes. A specific fragment was amplified from 60 of 66 serotypes. An amplification product was not observed from coxsackievirus types A11, A17, and A24 and echovirus types 16, 22, and 23. Enteroviral RNA was detected by the PCR in routinely collected throat swabs and stool specimens that were found to be positive for enterovirus by isolation in tissue culture. Enteroviral RNA was detected in one of five myocardial biopsy specimens from patients with dilated cardiomyopathy, implicating virus persistence. No amplification product was obtained from eight control samples. Our results demonstrate the significance of the PCR for the detection of enteroviral RNA and, in particular, for the demonstration of persistent enteroviral infections.
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            The eradication of polio--progress and challenges.

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              Certification of poliomyelitis eradication. WHO Western Pacific Region, October 2000.

              (2000)
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                Author and article information

                Journal
                Emerg Infect Dis
                EID
                Emerging Infectious Diseases
                Centers for Disease Control and Prevention
                1080-6040
                1080-6059
                January 2009
                : 15
                : 1
                : 63-65
                Affiliations
                [1]Eastern Health, Melbourne, Victoria, Australia (A.J. Stewardson, C.L. Beckett, P.-S. Loh, J.R. Daffy)
                [2]Victorian Infectious Diseases Reference Laboratory, Melbourne (J.A. Roberts, B.R. Thorley)
                [3]MIA Victoria, Melbourne (H.T. Prime)
                Author notes
                Address for correspondence: Andrew J. Stewardson, Austin Hospital, PO Box 5555, Heidelberg 3084, Victoria, Australia; email: andrew.stew@ 123456rdson.net
                Article
                08-0791
                10.3201/eid1501.080791
                2660702
                19116053
                8cb06430-453d-4adb-a964-04f37be1b1ba
                History
                Categories
                Dispatch

                Infectious disease & Microbiology
                poliomyelitis,magnetic resonance imaging,human poliovirus 1,polymerase chain reaction

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