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Abstract
Oxidation and the production of free radicals are an integral part of aerobic metabolism.
A variety of reactive oxygen species (ROS) are produced by normal metabolic processes
and by certain leukocyte populations during defense against disease. Accumulated scientific
evidence supports the concept that oxidative damage of tissues and cellular components
are either a primary or secondary cause of many human diseases. Unfortunately, considerably
less is known about how oxidative stress can affect veterinary health and well-being,
particularly during times of high metabolic activity. The performance of high producing
dairy cattle can be optimized to a certain extent by supplementing diets with optimal
levels of micronutrients with antioxidant capabilities. However, oxidative stress
continues to be a problem in transition cows. Innovative approaches are needed to
enhance the antioxidant defense mechanisms of dairy cattle during times of increased
metabolic demands.