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      Advances of Optofluidic Microcavities for Microlasers and Biosensors

      review-article
      1 , 2 , *
      Micromachines
      MDPI
      microcavities, optofluidic dye lasers, whispering gallery modes, biosensors

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          Abstract

          Optofluidic microcavities with high Q factor have made rapid progress in recent years by using various micro-structures. On one hand, they are applied to microfluidic lasers with low excitation thresholds. On the other hand, they inspire the innovation of new biosensing devices with excellent performance. In this article, the recent advances in the microlaser research and the biochemical sensing field will be reviewed. The former will be categorized based on the structures of optical resonant cavities such as the Fabry–Pérot cavity and whispering gallery mode, and the latter will be classified based on the working principles into active sensors and passive sensors. Moreover, the difficulty of single-chip integration and recent endeavors will be briefly discussed.

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          Most cited references101

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          Parity–time symmetry and variable optical isolation in active–passive-coupled microresonators

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            Whispering gallery microcavity lasers

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              The potential of optofluidic biolasers.

              Optofluidic biolasers are emerging as a highly sensitive way to measure changes in biological molecules. Biolasers, which incorporate biological material into the gain medium and contain an optical cavity in a fluidic environment, can use the amplification that occurs during laser generation to quantify tiny changes in biological processes in the gain medium. We describe the principle of the optofluidic biolaser, review recent progress and provide our outlooks on potential applications and directions for developing this technology.
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                Author and article information

                Journal
                Micromachines (Basel)
                Micromachines (Basel)
                micromachines
                Micromachines
                MDPI
                2072-666X
                09 March 2018
                March 2018
                : 9
                : 3
                : 122
                Affiliations
                [1 ]College of Physics and Materials Engineering, Dalian Nationalities University, Dalian 116600, China; fzq@ 123456dlnu.edu.cn
                [2 ]College of Mechanical and Electronic Engineering, Dalian Nationalities University, Dalian 116600, China
                Author notes
                [* ]Correspondence: bailan@ 123456dlnu.edu.cn
                Article
                micromachines-09-00122
                10.3390/mi9030122
                6187242
                8d19ebab-6ff7-45a1-a0e3-422504bc8e28
                © 2018 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 29 January 2018
                : 06 March 2018
                Categories
                Review

                microcavities,optofluidic dye lasers,whispering gallery modes,biosensors

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