Contributors
Xi Luo: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
ValidationRole: VisualizationRole: Writing – original draftRole: Writing – review
& editing
Jill A. Rosenfeld:
ORCID: http://orcid.org/0000-0001-5664-7987
Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: ValidationRole:
VisualizationRole: Writing – original draftRole: Writing – review & editing
Shinya Yamamoto:
ORCID: http://orcid.org/0000-0003-2172-8036
Role: ConceptualizationRole: Funding acquisitionRole: MethodologyRole: SupervisionRole:
VisualizationRole: Writing – original draftRole: Writing – review & editing
Tamar Harel: Role: Formal analysisRole: InvestigationRole: Writing – review & editing
Zhongyuan Zuo: Role: Data curationRole: InvestigationRole: Writing – review & editing
Melissa Hall: Role: ResourcesRole: Writing – review & editing
Klaas J. Wierenga: Role: ResourcesRole: Writing – review & editing
Matthew T. Pastore:
ORCID: http://orcid.org/0000-0001-9888-0779
Role: ResourcesRole: Writing – review & editing
Dennis Bartholomew: Role: ResourcesRole: Writing – review & editing
Mauricio R. Delgado: Role: ResourcesRole: Writing – review & editing
Joshua Rotenberg: Role: ResourcesRole: Writing – review & editing
Richard Alan Lewis:
ORCID: http://orcid.org/0000-0002-6644-6385
Role: ResourcesRole: Writing – review & editing
Lisa Emrick: Role: ResourcesRole: Writing – review & editing
Carlos A. Bacino: Role: ResourcesRole: Writing – review & editing
Mohammad K. Eldomery: Role: InvestigationRole: Writing – review & editing
Zeynep Coban Akdemir:
ORCID: http://orcid.org/0000-0001-9928-9032
Role: InvestigationRole: Writing – review & editing
Fan Xia: Role: Data curationRole: InvestigationRole: Writing – review & editing
Yaping Yang: Role: Data curationRole: InvestigationRole: Writing – review & editing
Seema R. Lalani: Role: InvestigationRole: ResourcesRole: Writing – review & editing
Timothy Lotze: Role: InvestigationRole: ResourcesRole: Writing – review & editing
James R. Lupski: Role: ConceptualizationRole: Funding acquisitionRole: VisualizationRole: Writing –
review & editing
Brendan Lee:
ORCID: http://orcid.org/0000-0001-8573-4211
Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
SupervisionRole: VisualizationRole: Writing – original draftRole: Writing – review
& editing
Hugo J. Bellen: Role: ConceptualizationRole: Funding acquisitionRole: MethodologyRole: Project administrationRole:
SupervisionRole: VisualizationRole: Writing – original draftRole: Writing – review
& editing
Michael F. Wangler:
ORCID: http://orcid.org/0000-0001-5245-5910
Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: Project administrationRole: SupervisionRole: VisualizationRole: Writing
– original draftRole: Writing – review & editing
Bingwei Lu: Role: Editor
Journal
Journal ID (nlm-ta): PLoS Genet
Journal ID (iso-abbrev): PLoS Genet
Journal ID (publisher-id): plos
Journal ID (pmc): plosgen
Title:
PLoS Genetics
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7390
ISSN
(Electronic):
1553-7404
Publication date
(Electronic):
24
July
2017
Publication date Collection:
July
2017
Volume: 13
Issue: 7
Electronic Location Identifier: e1006905
Affiliations
[1
]
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,
United States of America
[2
]
Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston,
TX, United States of America
[3
]
Baylor-Hopkins Center for Mendelian Genomics, Department of Molecular and Human Genetics,
Baylor College of Medicine, Houston, TX, United States of America
[4
]
University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States of
America
[5
]
Nationwide Children’s Hospital & The Ohio State University, Columbus, OH, United States
of America
[6
]
Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center andTexas
Scottish Rite Hospital, Dallas, TX, United States of America
[7
]
Houston Specialty Clinic, Houston, TX, United States of America
[8
]
Department of Pediatrics, Baylor College of Medicine, Houston, TX, United States of
America
[9
]
Texas Children’s Hospital, Houston, TX, United States of America
[10
]
Howard Hughes Medical Institute, Houston TX, United States of America
Stanford University School of Medicine, UNITED STATES
Author notes
The Department of Molecular and Human Genetics at Baylor College of Medicine derives
revenue from molecular testing offered at the Baylor Genetics Laboratories. JRL has
stock ownership in 23 and Me, is a paid consultant for Regeneron Pharmaceuticals,
has stock options in Lasergen, Inc., and is a co-inventor on multiple United States
and European patents related to molecular diagnostics for inherited neuropathies,
eye diseases, and bacterial genomic fingerprinting.
¶ Membership of the UDN is provided in the supporting information.
Author information
Article
Publisher ID:
PGENETICS-D-17-00669
DOI: 10.1371/journal.pgen.1006905
PMC ID: 5557584
PubMed ID: 28742085
SO-VID: 8d626f55-ea55-498e-b4da-92e02a78ac99
Copyright © © 2017 Luo et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 3
April
2017
Date
accepted
: 3
July
2017
Page count
Figures: 5,
Tables: 1,
Pages: 20
Funding
Funded by: funder-id http://dx.doi.org/10.13039/100000065, National Institute of Neurological Disorders and Stroke;
Award ID: U54NS093793
Award Recipient
:
Hugo J. Bellen
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: R24OD022005
Award Recipient
:
Hugo J. Bellen
Funded by: funder-id http://dx.doi.org/10.13039/100000057, National Institute of General Medical Sciences;
Award ID: R01GM067858
Award Recipient
:
Hugo J. Bellen
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: U01HG007709
Award Recipient
:
ORCID: http://orcid.org/0000-0001-8573-4211
Brendan Lee
Funded by: funder-id http://dx.doi.org/10.13039/100000051, National Human Genome Research Institute;
Award ID: UM1 HG006542
Award Recipient
:
James R. Lupski
Funded by: funder-id http://dx.doi.org/10.13039/100000011, Howard Hughes Medical Institute;
Award ID: N/A
Award Recipient
:
Hugo J. Bellen
Funded by: funder-id http://dx.doi.org/10.13039/100000893, Simons Foundation;
Award ID: 368479
Award Recipient
:
ORCID: http://orcid.org/0000-0001-5245-5910
Michael F. Wangler
Funded by: Michael Fund International Foundation for Genetics Research (US)
Award Recipient
:
ORCID: http://orcid.org/0000-0002-6644-6385
Richard Alan Lewis
This work was supported in part by NIH grants U54NS093793, R24OD022005, and R01GM067858
to HJB, by U01HG007709 to BL, by UM1 HG006542 to JRL, and by Simons Foundation Functional
Screen (368479 to MFW). RAL is supported in part by the Genetic Resource Association
of Texas (GReAT). HJB is an investigator of the Howard Hughes Medical Institute (HHMI).
In addition, funding was received by NIH/NIGMS T32 GM007526 to BL and NIH/NICHD U54
HD083092 for Intellectual and Developmental Disabilities Research Center (IDDRC).
The sponsors and funding agencies had no role in study design, data collection and
analysis, decision to publish or preparation of the manuscript.
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