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      Effect of Hormonal Environment on Sterol Concentrations of Rat Aorta and Plasma


      Hormone Research in Paediatrics

      S. Karger AG

      Rats, Aorta, Plasma, Cholesterol, Cholesterol ester, Atherosclerosis

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          Cholesterol and cholesterol esters were measured on day 90 in the plasma and aortas of rats treated on day 4 as follows: control, gonadectomy, testosterone propionate (TP), estradiol-17 β (E). Sex differences were observed in sterol concentrations of control animals but were abolished by castration. TP and E significantly altered sex gland weights, aorta cholesterol and plasma cholesterol esters of both sexes. Little effect on plasma cholesterol or esterified cholesterol of the aorta was noted in any treatment group. A dose effect of E was observed in organ weights and sterols of male rats.

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          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          21 November 2008
          : 6
          : 1
          : 2-11
          Department of Biology, University of Southern Mississippi, Hattiesburg, Miss.
          178656 Horm Res 1975;6:2–11
          © 1975 S. Karger AG, Basel

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          Page count
          Pages: 10
          Original Paper


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