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      Efficacy of transoral fundoplication vs omeprazole for treatment of regurgitation in a randomized controlled trial.

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          Abstract

          Transoral esophagogastric fundoplication (TF) can decrease or eliminate features of gastroesophageal reflux disease (GERD) in some patients whose symptoms persist despite proton pump inhibitor (PPI) therapy. We performed a prospective, sham-controlled trial to determine if TF reduced troublesome regurgitation to a greater extent than PPIs in patients with GERD.

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          Author and article information

          Journal
          Gastroenterology
          Gastroenterology
          1528-0012
          0016-5085
          Feb 2015
          : 148
          : 2
          Affiliations
          [1 ] Department of Surgery, Oregon Health & Science University, Portland, Oregon. Electronic address: hunterj@ohsu.edu.
          [2 ] Department of Surgery and Department of Gastroenterology, Northwestern University, Chicago, Illinois.
          [3 ] SurgOne Foregut Institute, Englewood, Colorado.
          [4 ] Department of Surgery, University of Texas Health Science Center, Houston, Texas.
          [5 ] Department of Surgery, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia; Reston Surgical Associates, Reston, Virginia.
          [6 ] Department of Surgery, Oregon Health & Science University, Portland, Oregon.
          [7 ] Department of Surgery, The Ohio State University, Columbus, Ohio.
          [8 ] Department of Surgery, University of Washington, Seattle, Washington.
          [9 ] Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California.
          [10 ] Department of Surgery, Oregon Health & Science University, Portland, Oregon; Department of Surgery, Oregon Clinic, Portland, Oregon.
          Article
          S0016-5085(14)01208-6
          10.1053/j.gastro.2014.10.009
          25448925
          8e180fd9-ea66-47a8-bd85-676d2d80b1fb
          Copyright © 2015 AGA Institute. Published by Elsevier Inc. All rights reserved.
          History

          Esophagus,EsophyX,Stomach,TIF
          Esophagus, EsophyX, Stomach, TIF

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