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Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhoea: a multicentre study.

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      Abstract

      Childhood diarrhoea can be caused by many pathogens that are difficult to assay in the laboratory. Molecular diagnostic techniques provide a uniform method to detect and quantify candidate enteropathogens. We aimed to develop and assess molecular tests for identification of enteropathogens and their association with disease.

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      Affiliations
      [1 ] Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA.
      [2 ] Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
      [3 ] Medical Research Council Unit, Banjul, The Gambia.
      [4 ] Department of Enteric Diseases, Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand.
      [5 ] International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR, B), Dhaka, Bangladesh.
      [6 ] Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA; Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
      [7 ] Department of Pathology, University of Virginia, Charlottesville, VA, USA.
      [8 ] Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
      [9 ] Haydom Lutheran Hospital, Haydom, Tanzania.
      [10 ] Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA. Electronic address: erh6k@virginia.edu.
      Journal
      Lancet Infect Dis
      The Lancet. Infectious diseases
      1474-4457
      1473-3099
      Aug 2014
      : 14
      : 8
      S1473-3099(14)70808-4 10.1016/S1473-3099(14)70808-4 25022434
      Copyright © 2014 Elsevier Ltd. All rights reserved.

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