For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
10
views
15
references
 Top references
cited by
11
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      0
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      18F-FDG PET/CT in the Diagnosis and Management of Continuous Flow Left Ventricular Assist Device Infections: A Case Series and Review of the Literature

      case-report

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Supplemental Digital Content is available in the text.

          Abstract

          Implantable continuous flow left ventricular assist devices (LVADs) are increasingly used in end-stage heart failure treatment as a bridge-to-transplant and destination therapy (DT). However, LVADs still have major drawbacks, such as infections that can cause morbidity and mortality. Unfortunately, appropriate diagnosis of LVAD-related and LVAD-specific infections can be very cumbersome. The differentiation between deep and superficial infections is crucial in clinical decision-making. Despite a decade of experience in using fluorodeoxyglucose positron emission tomography/computed tomography ( 18F-FDG PET/CT) to diagnose various infections, its use in LVAD patients remains scarce. In this case series, we review the current evidence in literature and describe our single center experience using 18F-FDG PET/CT for the diagnosis and management of LVAD infections.

          Related collections

          Most cited references15

          • Record: found
          • Abstract: found
          • Article: not found

          FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0

          Ronald Boellaard, Roberto Delgado-Bolton, Wim Oyen … (2014)
          The purpose of these guidelines is to assist physicians in recommending, performing, interpreting and reporting the results of FDG PET/CT for oncological imaging of adult patients. PET is a quantitative imaging technique and therefore requires a common quality control (QC)/quality assurance (QA) procedure to maintain the accuracy and precision of quantitation. Repeatability and reproducibility are two essential requirements for any quantitative measurement and/or imaging biomarker. Repeatability relates to the uncertainty in obtaining the same result in the same patient when he or she is examined more than once on the same system. However, imaging biomarkers should also have adequate reproducibility, i.e. the ability to yield the same result in the same patient when that patient is examined on different systems and at different imaging sites. Adequate repeatability and reproducibility are essential for the clinical management of patients and the use of FDG PET/CT within multicentre trials. A common standardised imaging procedure will help promote the appropriate use of FDG PET/CT imaging and increase the value of publications and, therefore, their contribution to evidence-based medicine. Moreover, consistency in numerical values between platforms and institutes that acquire the data will potentially enhance the role of semiquantitative and quantitative image interpretation. Precision and accuracy are additionally important as FDG PET/CT is used to evaluate tumour response as well as for diagnosis, prognosis and staging. Therefore both the previous and these new guidelines specifically aim to achieve standardised uptake value harmonisation in multicentre settings.
          Article 0 comments Cited 603 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Advanced heart failure treated with continuous-flow left ventricular assist device.

            V Conte, Stuart D. Russell, D Farrar … (2009)
            Patients with advanced heart failure have improved survival rates and quality of life when treated with implanted pulsatile-flow left ventricular assist devices as compared with medical therapy. New continuous-flow devices are smaller and may be more durable than the pulsatile-flow devices. In this randomized trial, we enrolled patients with advanced heart failure who were ineligible for transplantation, in a 2:1 ratio, to undergo implantation of a continuous-flow device (134 patients) or the currently approved pulsatile-flow device (66 patients). The primary composite end point was, at 2 years, survival free from disabling stroke and reoperation to repair or replace the device. Secondary end points included survival, frequency of adverse events, the quality of life, and functional capacity. Preoperative characteristics were similar in the two treatment groups, with a median age of 64 years (range, 26 to 81), a mean left ventricular ejection fraction of 17%, and nearly 80% of patients receiving intravenous inotropic agents. The primary composite end point was achieved in more patients with continuous-flow devices than with pulsatile-flow devices (62 of 134 [46%] vs. 7 of 66 [11%]; P<0.001; hazard ratio, 0.38; 95% confidence interval, 0.27 to 0.54; P<0.001), and patients with continuous-flow devices had superior actuarial survival rates at 2 years (58% vs. 24%, P=0.008). Adverse events and device replacements were less frequent in patients with the continuous-flow device. The quality of life and functional capacity improved significantly in both groups. Treatment with a continuous-flow left ventricular assist device in patients with advanced heart failure significantly improved the probability of survival free from stroke and device failure at 2 years as compared with a pulsatile device. Both devices significantly improved the quality of life and functional capacity. (ClinicalTrials.gov number, NCT00121485.) 2009 Massachusetts Medical Society
            Article 0 comments Cited 171 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              EANM/SNMMI guideline for 18F-FDG use in inflammation and infection.

              Josep Comin-Colet, John Buscombe, Timothy J Donohoe … (2013)
              Article 0 comments Cited 89 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): ASAIO J
                Journal ID (iso-abbrev): ASAIO J
                Journal ID (publisher-id): MAT
                Title: Asaio Journal
                Publisher: Lippincott Williams & Wilkins
                ISSN (Print): 1058-2916
                ISSN (Electronic): 1538-943X
                Publication date (Print): March 2018
                Publication date (Electronic): 23 February 2018
                Volume: 64
                Issue: 2
                Pages: e11-e19
                Affiliations
                From the [* ]Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; [† ]Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; [‡ ]Department of Cardiothoracic Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; and [§ ]Department of Radiology & Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
                Author notes
                Correspondence: Sakir Akin, Erasmus MC, Department of Cardiology and Department of Intensive Care, University Medical Center Rotterdam, Thoraxcenter, Room Ba577, ‘s-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands. Email: s.akin@ 123456erasmusmc.nl .
                Article
                Accession ID: 00023
                DOI: 10.1097/MAT.0000000000000552
                PMC ID: 5839716
                PubMed ID: 28234643
                SO-VID: 8e997b02-1f7f-4ac6-a1a4-793d8c45cff0
                Copyright © Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the ASAIO.
                License:

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

                History
                Categories
                Subject: Case Reports
                Custom metadata
                OPEN-ACCESS TRUE
                SDC T

                Keywords: left ventricular assist devices,infection,18f-fdg pet/ct
                Data availability:
                Keywords: left ventricular assist devices, infection, 18f-fdg pet/ct

                Comments

                Comment on this article