High prevalence and widely distribution of liver fluke remain an important public health problem in China and some countries in southeast Asia. Liver fluke, which causes human clonorchiasis or human opisthorchiasis, includes Clonorchis sinensis, Opisthorchis viverrini, Opisthorchis felineus. Clonorchis sinensis is the most widely infected and distribution human parasite of the three in term of population. The second most common species is O. viverrini in Mekong river basin. Both of them are associated with the development of human cholangiocarcinoma. Although the government has invested a lot of manpower, material and financial resources, the infection rate of liver fluke in some province tends to be increasing with time, suggesting that there is a long way to control the prevalent of the flukes. Here, we reviewed the progress of Clonorchiasis and Opithorchiasis in the field of prevalence, diagnosis, prevention and control, and emphasized the difficult and key points in the prevention and control of both worms in the future.
摘要： 肝吸虫流行范围广、感染率高, 是目前我国和部分东南亚国家重要的公共卫生问题。可引起人类肝吸虫病 的肝吸虫包括华支睾吸虫、麝猫后睾吸虫和猫后睾吸虫, 流行于我国的华支睾吸虫感染人数最多, 流行于湄公河流域 的麝猫后睾吸虫次之, 两者都与胆管癌的发生有关。尽管政府对肝吸虫防控工作投入了大量的人力、物力和财力, 但 是我国部分省肝吸虫感染率有随时间增高趋势, 说明肝吸虫防控工作任重道远。本文针对华支睾吸虫病和麝猫后睾 吸虫病的病原学检测和诊断、传播和流行、以及防控等现状进行综述, 指出了未来肝吸虫病防控工作的重点和难点。