A study of pseudoexfoliation syndrome frequency has been evaluated in the northwest of Greece (Epirus). In 700 examined patients (greater than or equal to 50 years old) pseudoexfoliation was found in 170 (24.3%). The frequency of pseudoexfoliation increases with age; no difference was noticed between sexes. Ocular hypertension (greater than 22 mmHg) was found in 39.5% of the patients.