Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
20
October
2016
Publication date Collection: 2016
Volume: 11
Issue: 10
Electronic Location Identifier: e0165182
Affiliations
[1
]Department of Anesthesiology and Critical Care, Medical Center – University of Freiburg,
Faculty of Medicine, University of Freiburg, Freiburg, Germany
[2
]Eye Center, Medical Center – University of Freiburg, Faculty of Medicine, University
of Freiburg, Freiburg, Germany
[3
]Instituto de Tecnologia Química e Biológica-António Xavier, Universidade Nova de Lisboa,
Oeiras, Portugal
[4
]Alfama Ltd., Instituto de Biologia Experimental e Tecnológica, IBET, Oeiras, Portugal
Indian Institute of Science Education and Research, INDIA
Author notes
Competing Interests: We have the following interests: The co-author Carlos C. Romão is a co-founder, administrator
and scientific officer of the company Alfama Lda. where he has equity interests. Carlos
C. Romão is an inventor of Patent-No.: US 2011/0038955 A1 2011, where ALF-186 exemplifies
the protection of the stomach against NSAID generated ulcers by the administration
of CORMs, and is therefore irrelevant for the matter of the present article. The drug
profile of ALF-186 is published in detail in: Dalton Transactions DOI:
10.1039/c2dt32174b. "Alfama Ltd. provided support in supplying C.C.R. with the ALF-186 compound, which
is not commercially available. There are no further patents, products in development
or marketed products to declare. This does not alter our adherence to all the PLOS
ONE policies on sharing data and materials, as detailed online in the guide for authors.
-
Conceptualization: JB UG.
-
-
Formal analysis: FU KBK AM WAL MA HB CCR JB UG.
-
Funding acquisition: JB UG.
-
Investigation: FU KBK AM MA.
-
Methodology: WAL MA JB UG.
-
Project administration: JB UG.
-
Resources: WAL HB CCR JB UG.
-
-
Validation: FU KBK AM WAL MA HB CCR JB UG.
-
-
Writing – original draft: FU KBK AM WAL MA HB CCR JB UG.
-
Writing – review & editing: FU KBK AM WAL MA HB CCR JB UG.
Author information
Article
Publisher ID:
PONE-D-16-17732
DOI: 10.1371/journal.pone.0165182
PMC ID: 5072679
PubMed ID: 27764224
SO-VID: 8ec941c7-fcdf-4334-b9b4-15742efe03de
Copyright © © 2016 Ulbrich et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100001659, Deutsche Forschungsgemeinschaft;
Award ID: Go 2158/3-1
Award Recipient
:
ORCID: http://orcid.org/0000-0002-9991-3226
Ulrich Goebel
Funded by: funder-id http://dx.doi.org/10.13039/501100001659, Deutsche Forschungsgemeinschaft;
Award ID: Bi 1567/2-1
Award Recipient
:
Julia Biermann
Funded by: Alfama Ltd.
Award Recipient
:
Carlos C. Ramao
This work was conducted at the Department of Anesthesiology and Intensive Care, Medical
Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany and granted
by The German Research Foundation (DFG, Grants: Go 2158/3-1 and Bi 1567/2-1). The
funder had no role in study design, data collection and analysis, decision to publish
or preparation of the manuscript. Alfama Ltd. provided support in the form of supplying
Carlos C. Romão with the ALF-186 compound - which is not commercially available -
but did not have any additional role in the study design, data collection and analysis,
decision to publish, or preparation of the manuscript. The specific role of this author
is articulated in the 'author contributions' section.
Subject:
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Biology and Life Sciences
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Cell Biology
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Cellular Types
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Animal Cells
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Neurons
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Afferent Neurons
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Retinal Ganglion Cells
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Biology and Life Sciences
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Neuroscience
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Cellular Neuroscience
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Neurons
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Afferent Neurons
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Retinal Ganglion Cells
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Biology and Life Sciences
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Cell Biology
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Cellular Types
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Animal Cells
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Neurons
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Ganglion Cells
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Retinal Ganglion Cells
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Biology and Life Sciences
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Neuroscience
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Cellular Neuroscience
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Neurons
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Ganglion Cells
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Retinal Ganglion Cells
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Cell Biology
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Cell Processes
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Cell Death
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Molecular Biology Techniques
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Molecular Biology Assays and Analysis Techniques
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