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      Liver regeneration.

      Journal of Cellular Physiology

      Animals, Epithelial Cells, metabolism, Hemodynamics, Hepatectomy, Hepatocytes, Humans, Interleukin-6, Liver, cytology, embryology, physiology, Liver Regeneration, Mitosis, Signal Transduction, Stem Cells, Transforming Growth Factor beta1

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          Abstract

          Liver regeneration after partial hepatectomy is a very complex and well-orchestrated phenomenon. It is carried out by the participation of all mature liver cell types. The process is associated with signaling cascades involving growth factors, cytokines, matrix remodeling, and several feedbacks of stimulation and inhibition of growth related signals. Liver manages to restore any lost mass and adjust its size to that of the organism, while at the same time providing full support for body homeostasis during the entire regenerative process. In situations when hepatocytes or biliary cells are blocked from regeneration, these cell types can function as facultative stem cells for each other.

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          Journal
          17559071
          2701258
          10.1002/jcp.21172

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