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      Efficacy, Tolerability, and Dose-Dependent Effects of Opioid Analgesics for Low Back Pain : A Systematic Review and Meta-analysis

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          Abstract

          Opioid analgesics are commonly used for low back pain, however, to our knowledge there has been no systematic evaluation of the effect of opioid dose and use of enrichment study design on estimates of treatment effect.

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          Author and article information

          Journal
          JAMA Internal Medicine
          JAMA Intern Med
          American Medical Association (AMA)
          2168-6106
          July 01 2016
          July 01 2016
          : 176
          : 7
          : 958
          Affiliations
          [1 ]The George Institute for Global Health, Sydney, Australia2School of Medicine, Western Sydney University, Penrith, Australia
          [2 ]Musculoskeletal Division, The George Institute for Global Health, Sydney, Australia4Sydney Medical School, University of Sydney, Sydney, Australia
          [3 ]Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia
          [4 ]Department of Clinical Pharmacology, St Vincent’s Hospital and St Vincent’s Clinical School, University of New South Wales, Sydney, Australia7School of Medical Sciences, University of New South Wales, Sydney, Australia
          [5 ]The George Institute for Global Health, Sydney, Australia8Centre for Education and Research on Ageing, Sydney, Australia
          Article
          10.1001/jamainternmed.2016.1251
          27213267
          8f12e09c-ce9d-450f-9694-9ecb0a67e7f9
          © 2016
          History

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