Tyrosine kinase inhibitor-induced vasculopathy in clear cell renal cell carcinoma: an unrecognized antitumour mechanism.

Tsuzuki, Toyonori; SASSA, NAOTO; Shimoyama, Yoshie; Morikawa, Takamitsu J.; Shiroki, Ryoichi; Kuroda, Makoto; Fukatsu, Akitoshi; Kuwahara-Arai, Kyoko; YOSHINO, YASUSHI; Hattori, Ryohei; GOTOH, MOMOKAZU

doi:10.1111/his.12277

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Tyrosine kinase inhibitor-induced vasculopathy in clear cell renal cell carcinoma: an unrecognized antitumour mechanism.

Author(s): Toyonori Tsuzuki ¹ , Naoto Sassa , Yoshie Shimoyama , Takamitsu Morikawa , Ryoichi Shiroki , Makoto Kuroda , Akitoshi Fukatsu , Kyoko Kuwahara , Yasushi Yoshino , Ryohei Hattori , Momokazu Gotoh

Publication date (Electronic): Mar 2014

Journal: Histopathology

Keywords: antitumour mechanism, clear cell renal cell carcinoma, tyrosine kinase inhibitor, vasculopathy

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Abstract

To evaluate the pathological features of clear cell renal cell carcinoma (CCRCC) treated with tyrosine kinase inhibitors (TKIs), and to elucidate the mechanism of action of TKIs.

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Journal ID (iso-abbrev): Histopathology

Title: Histopathology

ISSN (Electronic): 1365-2559

ISSN (Print): 0309-0167

Publication date (Electronic): Mar 2014

Volume: 64

Issue: 4

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[1 ] Department of Pathology, Nagoya Daini Red Cross Hospital, Nagoya, Japan.

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DOI: 10.1111/his.12277

PubMed ID: 24274732

SO-VID: 8f3b6fd5-0549-42ab-a6ba-db71e92bbb41

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Keywords: antitumour mechanism,clear cell renal cell carcinoma,tyrosine kinase inhibitor,vasculopathy

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Keywords: antitumour mechanism, clear cell renal cell carcinoma, tyrosine kinase inhibitor, vasculopathy

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Tyrosine kinase inhibitor-induced vasculopathy in clear cell renal cell carcinoma: an unrecognized antitumour mechanism.

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