69
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Multi-Mycotoxin Screening Reveals the Occurrence of 139 Different Secondary Metabolites in Feed and Feed Ingredients

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The development of liquid chromatography-mass spectrometry (LC-MS)/mass spectrometry (MS) methods for the simultaneous detection and quantification of a broad spectrum of mycotoxins has facilitated the screening of a larger number of samples for contamination with a wide array of less well-known “emerging” mycotoxins and other metabolites. In this study, 83 samples of feed and feed raw materials were analysed. All of them were found to contain seven to 69 metabolites. The total number of detected metabolites amounts to 139. Fusarium mycotoxins were most common, but a number of Alternaria toxins also occurred very often. Furthermore, two so-called masked mycotoxins ( i.e., mycotoxin conjugates), namely deoxynivalenol-3-glucoside (75% positives) and zearalenone-4-sulfate (49% positives), were frequently detected. Although the observed median concentrations of the individual analytes were generally in the low μg/kg range, evaluating the toxicological potential of a given sample is difficult. Toxicity data on less well-known mycotoxins and other detected metabolites are notoriously scarce, as an overview on the available information on the most commonly detected metabolites shows. Besides, the possible synergistic effects of co-occurring substances have to be considered.

          Related collections

          Most cited references93

          • Record: found
          • Abstract: not found
          • Article: not found

          Mycotoxin contamination of the feed supply chain: Implications for animal productivity and feed security

            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Worldwide occurrence of mycotoxins in commodities, feeds and feed ingredients

              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins

                Bookmark

                Author and article information

                Journal
                Toxins (Basel)
                Toxins (Basel)
                toxins
                Toxins
                MDPI
                2072-6651
                08 March 2013
                March 2013
                : 5
                : 3
                : 504-523
                Affiliations
                [1 ]BIOMIN Research Center, Technopark 1, Tulln 3430, Austria; E-Mails: elisabeth.streit@ 123456biomin.net (E.S.); gerd.schatzmayr@ 123456biomin.net (G.S.)
                [2 ]BIOMIN Holding GmbH, Industriestrasse 21, Herzogenburg 3130, Austria; E-Mail: karin.naehrer@ 123456biomin.net
                [3 ]Center for Analytical Chemistry, Department for Agrobiotechnology (IFA-Tulln), University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad-Lorenz-Str. 20, Tulln 3430, Austria; E-Mails: michael.sulyok@ 123456boku.ac.at (M.S.); rudolf.krska@ 123456boku.ac.at (R.K.)
                Author notes
                [* ] Author to whom correspondence should be addressed; E-Mail: christina.schwab@ 123456biomin.net ; Tel.: +43-2782-803-320; Fax: +43-2782-803-40.
                Article
                toxins-05-00504
                10.3390/toxins5030504
                3705275
                23529186
                8f3c0bc6-7248-4655-978b-1349fd1ed872
                © 2013 by the authors; licensee MDPI, Basel, Switzerland.

                This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/3.0/).

                History
                : 14 December 2012
                : 07 February 2013
                : 22 February 2013
                Categories
                Article

                Molecular medicine
                emerging mycotoxins,masked mycotoxins,liquid chromatography,mass spectrometry,lc-ms/ms,mould

                Comments

                Comment on this article