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      Results from in vitro Fertilization and Intracytoplasmic Sperm Injection with Purified Gonadotrophins (Metrodin HP®)

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          Purified urinary follicle-stimulating hormone (uFSH-HP; Metrodin HP®, Serono Ltd.) was compared with a combination of pure FSH and human menopausal gonadotrophin (hMG; Pergonal®, Serono Ltd.) in patients undergoing standard in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). In standard IVF, pure FSH gave a significantly higher pregnancy rate per started cycle than did the combination with hMG (35 vs. 18%, p < 0.05). No differences between standard IVF and ICSI were seen which could be associated with hormonal stimulation in an open non-randomized series of patients. In 11 ICSI cycles, the use of recombinant FSH (Gonal F®, Serono Ltd.) resulted in 4 ongoing pregnancies.

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          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          05 December 2008
          : 43
          : 5
          : 238-240
          aFertility Center Scandinavia, Carlander’s Hospital, Göteborg, and bDepartment of Obstetrics and Gynecology, University of Göteborg, Sweden
          184286 Horm Res 1995;43:238–240
          © 1995 S. Karger AG, Basel

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          Page count
          Pages: 3
          Proceedings of the Ares Serono Satellite Symposium


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