Pediatric patients with urinary tract infection (UTI) undergo imaging tests to detect vesicoureteral reflux (VUR) in the belief that VUR correlates to risk of renal scarring. This article describes recent evolution and controversies in the management of UTI and VUR. Multitechnique imaging of UTI and VUR is complex and controversial. Evolution in practice patterns is motivated by the desire to rationally minimize unnecessary interventions and radiation exposure. Ongoing evidence-based research is needed to further improve practice guidelines.