06 May 1998
Background/Aims: The present study was undertaken to analyze the β<sub>2</sub>-microglobulin (BMG)-removing efficiency of high-performance membranes (HPMs) in relation to changes in serum BMG levels after dialysis. Methods: In 10 stable dialysis patients, six different HPMs were used in a crossover method. Serum BMG levels were measured immediately before dialysis, immediately after, 4 h after, and immediately before the next dialysis. On the basis of these measurements, the BMG removal rate was calculated. Results: The BMG removal rate as calculated on the basis of the BMG level immediately after dialysis was 11.29% higher than the rate calculated on the basis of the BMG level 4 h after dialysis. Conclusion: The BMG removal rate can be overestimated if it is calculated on the basis of the BMG level immediately after dialysis.