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      Removal of Serum Beta-2 Microglobulin Using High-Performance Membranes and Analysis of Changes in Serum BMG Levels after Dialysis

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          Abstract

          Background/Aims: The present study was undertaken to analyze the β<sub>2</sub>-microglobulin (BMG)-removing efficiency of high-performance membranes (HPMs) in relation to changes in serum BMG levels after dialysis. Methods: In 10 stable dialysis patients, six different HPMs were used in a crossover method. Serum BMG levels were measured immediately before dialysis, immediately after, 4 h after, and immediately before the next dialysis. On the basis of these measurements, the BMG removal rate was calculated. Results: The BMG removal rate as calculated on the basis of the BMG level immediately after dialysis was 11.29% higher than the rate calculated on the basis of the BMG level 4 h after dialysis. Conclusion: The BMG removal rate can be overestimated if it is calculated on the basis of the BMG level immediately after dialysis.

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          Author and article information

          Journal
          AJN
          Am J Nephrol
          10.1159/issn.0250-8095
          American Journal of Nephrology
          S. Karger AG
          0250-8095
          1421-9670
          1998
          June 1998
          06 May 1998
          : 18
          : 3
          : 228-232
          Affiliations
          a 2nd Division of Internal Medicine, Kansai Medical University, Kohori Hospital and b Nakamura Clinic, Neyagawa, Osaka, Japan
          Article
          13341 Am J Nephrol 1998;18:228–232
          10.1159/000013341
          9627039
          © 1998 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Figures: 6, Tables: 2, References: 11, Pages: 5
          Product
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/13341
          Categories
          Clinical Study

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