Blog
About

  • Record: found
  • Abstract: not found
  • Article: not found

Data sharing: Empty archives

Nature

Springer Science and Business Media LLC

Read this article at

ScienceOpenPublisher
Bookmark
      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

      Related collections

      Most cited references 3

      • Record: found
      • Abstract: not found
      • Article: not found

      Understanding Faculty to Improve Content Recruitment for Institutional Repositories

        Bookmark
        • Record: found
        • Abstract: not found
        • Article: not found

        Epidemiology, data sharing, and the challenge of scientific replication.

          Bookmark
          • Record: found
          • Abstract: found
          • Article: not found

          DNA repair and colorectal cancer.

          The mismatch repair system plays a major role in the processing of recombination intermediates and in the repair of errors made during DNA replication or resulting from chemical damage to DNA. Human homologues of the bacterial and yeast mismatch repair genes have been recently identified, and mutations in these genes have been found to show risk for tumor development in hereditary nonpolyposis colorectal cancer syndrome (HNPCC). Colorectal tumors bearing homozygous mutations in these mismatch repair genes show a hypermutable phenotype, mainly at microsatellite regions of DNA. The temporal relationship between the loss of mismatch repair activity and the cascades of mutations in critical genes involved in the carcinogenesis of HNPCC tumors is unknown.
            Bookmark

            Author and article information

            Journal
            Nature
            Nature
            Springer Science and Business Media LLC
            0028-0836
            1476-4687
            September 2009
            September 9 2009
            September 2009
            : 461
            : 7261
            : 160-163
            10.1038/461160a
            © 2009

            http://www.springer.com/tdm

            Comments

            Comment on this article