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      The Effect of Low Magnesium Dialysate on Plasma, Ultrafiltrable, Erythrocyte and Bone Magnesium Concentrations from Patients on Maintenance Haemodialysis

      , ,

      Nephron

      S. Karger AG

      Chronic renal failure, Haemodialysis, Magnesium, Erythrocytes, Bone

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          Abstract

          Dialysis fluid containing a low concentration of magnesium ( ≤ 0.05 mmol/l) was used to treat 17 patients on maintenance haemodialysis for varying periods of time up to 5 years. Mean plasma and ultrafiltrable magnesium concentrations measured in these patients before haemodialysis did not differ significantly from control values; after dialysis, plasma and ultrafiltrable magnesium concentrations were reduced only temporarily. Erythrocyte magnesium concentrations were elevated both before and after haemodialysis: dialysis did not significantly alter the mean concentrations. There was no significant correlation between the length of time on maintenance haemodialysis and either plasma or erythrocyte magnesium levels. As the mean magnesium concentration of bone biopsy specimens was also significantly greater than the mean from the control subjects, there was no evidence that magnesium depletion had been produced in these dialysis patients.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1974
          1974
          28 November 2008
          : 13
          : 5
          : 372-381
          Affiliations
          Departments of Medicine and Chemical Pathology, University of Aberdeen, Aberdeen
          Article
          180413 Nephron 1974;13:372–381
          10.1159/000180413
          4431548
          © 1974 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 10
          Categories
          Paper

          Cardiovascular Medicine, Nephrology

          Chronic renal failure, Haemodialysis, Magnesium, Erythrocytes, Bone

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