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Positive correlation between Beta-3-Adrenergic Receptor (ADRB3) gene and gout in a Chinese male population.
Binbin Wang
1 ,
Dongmei Meng ,
Jing Wang ,
Zhaotong Jia ,
Sirui Zhoub ,
Shiguo Liu ,
Nan Chu ,
Lin Han ,
Kun Zhang ,
Xu Ma ,
Changgui Li
Apr 2011
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Abstract
The common polymorphism rs4994 [c. T387C, p. Trp64Arg (W64R)] of the lipolysis regulator beta-3-adrenergic receptor (ADRB3) was identified as a marker in the pathogenesis of hyperuricemia. As gout is characterized by elevated serum concentrations of uric acid, we investigated ADRB3 as a potential candidate for gout.