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      Molecular hybridization of radioactive DNA to the DNA of cytological preparations.

      Proceedings of the National Academy of Sciences of the United States of America

      Animals, Autoradiography, DNA, Female, Hybridization, Genetic, Methods, Mice, Ovum, Thymidine, metabolism, Tritium

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          Abstract

          A method is presented for detecting the cellular location of specific DNA fractions. The technique involves the hybridization of a radioactive test DNA in solution to the stationary DNA of a cytological preparation. Sites of DNA binding are then detected by autoradiography. Experiments with DNA of the toad Xenopus are described.

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          Journal
          5261036
          223386

          Chemistry

          Animals, Autoradiography, DNA, Female, Hybridization, Genetic, Methods, Mice, Ovum, Thymidine, metabolism, Tritium

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